Managing obesity in adults and adolescents 12 years and older. It is also used to reduce the risk of weight regain after previous weight loss.

Xenical is a gastrointestinal lipase inhibitor. It works by inhibiting the digestion of fats from the diet and should be used with a reduced-calorie diet.

Some medical conditions may interact with Xenical . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have an underactive thyroid

Some MEDICINES MAY INTERACT with Xenical . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticoagulants (eg, warfarin) because side effects, including risk of bleeding, may be increased by Xenical
• Cyclosporine because its effectiveness may be severely decreased by Xenical . Cyclosporine should be taken at least 2 hours before or after orlistat to ensure maximum absorption of cyclosporine into the bloodstream

This may not be a complete list of all interactions that may occur. Ask your health care provider if Xenical may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.